Home > Product > Antibody > Rabbit Anti-C21orf2/FITC Conjugated antibody
A2 antibody C21orf HUMF09G8.5; Chromosome 21 open reading frame 2; Hypothetical protein LOC755; Nuclear encoded mitochondrial protein cDNA A2 YF5; Uncharacterized protein C21orf2; YF 5; YF5; YF5/A2 antibody.
Cat:
SL9977R-FITC
Species Reactivity:
Human,Rat,(predicted: Mouse,)
Immunogen:
KLH conjugated synthetic peptide derived from human C21orf2
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
28kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf2 gene product has been provisionally designated C21orf2 pending further characterization.

Function:
May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization.

Similarity:
Contains 3 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
To C.elegans F09G8.5.

Database links:

Entrez Gene: 755 Human

Entrez Gene: 67884 Mouse

Omim: 603191 Human

SwissProt: O43822 Human

SwissProt: Q8C6G1 Mouse

Unigene: 517331 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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