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Rabbit Anti-C21orf2/FITC Conjugated antibody
background:
The smallest of the human chromosomes, 21 makes up about 1.5% of the human genome. Chromosome 21 contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias. The C21orf2 gene product has been provisionally designated C21orf2 pending further characterization.
Function:
May play roles in cilia formation and/or maintenance (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization.
Similarity:
Contains 3 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
To C.elegans F09G8.5.
Database links:
Entrez Gene: 755 Human
Entrez Gene: 67884 Mouse
Omim: 603191 Human
SwissProt: O43822 Human
SwissProt: Q8C6G1 Mouse
Unigene: 517331 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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