Home > Product > Antibody > Rabbit Anti-LCA5L/FITC Conjugated antibody
C21ORF13; Chromosome 21 open reading frame 13; Lca5l; LCA5L_HUMAN; Leber congenital amaurosis 5 like; Leber congenital amaurosis 5 like protein; Leber congenital amaurosis 5-like protein; Lebercilin-like protein.
Cat:
SL9972R-FITC
Species Reactivity:
Mouse,(predicted: Human,Rat,Pig,Cow,Horse,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human LCA5L
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
76kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Leber congenital amaurosis (LCA) is one of the most common causes of hereditary blindness or severe visual impairment in infants. Mutations in several genes with diverse functions mapping to two loci have been implicated in LCA causation. These proteins are involved in processes such as photoreceptor development and maintenance, phototransduction, vitamin A metabolism and protein trafficking. LCA5, also known as Lebercilin, is a ciliary protein that is widely expressed during development and localizes to the connecting cilia of photoreceptors and to the microtubules, centrioles and primary cilia of cultured mammalian cells. The Leber congenital amaurosis 5-like protein (LCA5L) is a 670 amino acid protein that belongs to the LCA5 family.

Similarity:
Belongs to the LCA5 family.

Database links:

Entrez Gene: 30082 Human

Entrez Gene: 385668 Mouse

SwissProt: O95447 Human

SwissProt: Q8C0X0 Mouse

Unigene: 517284 Human

Unigene: 24626 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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