Rabbit Anti-C20orf11/FITC Conjugated antibody

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Chromosome 20 open reading frame 11; CT011_HUMAN; Protein C20orf11; Twa1; Two hybrid associated protein 1; Two hybrid-associated protein 1 with Ran BP-M; Two hybrid associated protein 1 with RanBPM; Two hybrid-associated protein 1 with RanBPM.

Cat:

SL9689R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human TWA1/C20orf11

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

27kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
TWA1 is a 228 amino acid nuclear protein that is highly conserved throughout evolution. TWA1 interacts with Ran BP-M, a protein that is implicated in a diverse array of cellular processes including DNA replication, entry into and exit from mitosis, and the transport of RNA and proteins through the nuclear pore complex. Together, Ran BP-M and TWA1 form a complex with cytoplasmic Muskelin, a mediator of cell spreading. It is thought that this complex plays a role in the Ran GTPase cycle and therefore a potential role in the cell cycle. TWA1 contains a LisH-CTLH motif which is usually found in proteins that are involved in nucleokinesis, chromosome segregation, cell migration and microtubule dynamics. The gene encoding TWA1 maps to human chromosome 20, which comprises approximately 2% of the human genome and contains nearly 63 million bases that encode over 600 genes.

Subunit:
Interacts with RANBP9. Part of a complex consisting of RANBP9, MKLN1 and GID8.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the GID8 family.
Contains 1 CTLH domain.
Contains 1 LisH domain.

Database links:

Entrez Gene: 54994 Human

Omim: 611625 Human

SwissProt: Q9NWU2 Human

SwissProt: Q9D7M1 Mouse

Unigene: 353013 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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