background:
This gene encodes a member of the SLCtype lectin/SLCtype lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. This family member plays a role in cell-cell adhesion and angiogenesis. It functions in filopodia formation, cell migration and tube formation. Due to its presence at higher levels in tumor endothelium than in normal tissue endothelium, it is considered to be a candidate for tumor vascular targeting.
Subcellular Location:
Membrane; Single pass type I membrane protein.
Similarity:
Contains 1 SLCtype lectin domain.
Contains 1 EGF-like domain.
Database links:
Entrez Gene: 161198 Human
SwissProt: Q86T13 Human
Unigene: 525307 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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