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Rabbit Anti-C18orf1/FITC Conjugated antibody
background:
C18orf1 is a 306 amino acid single-pass membrane protein that contains one LDL-receptor class A domain and belongs to the PMEPA1 family. C18orf1 exists as five alternatively spliced isoforms that display selective expression and are encoded by a gene that maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.
Subcellular Location:
Cell membrane; Single-pass membrane protein (Potential).
Tissue Specificity:
Expressed in lymphocytes.
Similarity:
Belongs to the PMEPA1 family.
Contains 1 LDL-receptor class A domain.
Database links:
Entrez Gene: 753 Human
Omim: 606571 Human
SwissProt: O15165 Human
Unigene: 149363 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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