Home > Product > Antibody > Rabbit Anti-C16orf61/FITC Conjugated antibody
2310061C15Rik; Chromosome 16 open reading frame 61; DC13; Hypothetical protein LOC56942; COXM2_HUMAN.
Cat:
SL9627R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from human C16orf61
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
9kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The C16orf61 gene product has been provisionally designated C16orf61 pending further characterization

Function:
May be involved in cytochrome c oxidase biogenesis (By similarity).

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the CMC family.

Database links:

Entrez Gene: 56942 Human

Entrez Gene: 66531 Mouse

SwissProt: Q9NRP2 Human

SwissProt: Q8K199 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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