background:
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma levels of this hormone have been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain.
Function:
Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions.
The physiological role for the icosapeptide has not yet been elucidated.
Subunit:
Belongs to the NPY family.
Subcellular Location:
Secreted.
Similarity:
Belongs to the NPY family.
Database links:
Entrez Gene: 100064909 Horse
Entrez Gene: 5539 Human
Entrez Gene: 713988 Macaque Monkey
Omim: 167780 Human
SwissProt: P13610 Horse
SwissProt: P01298 Human
SwissProt: P33684 Macaque Monkey
Unigene: 558368 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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