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Rabbit Anti-C11orf73/FITC Conjugated antibody
background:
Required for organization and/or function of the secretory apparatus in Clara cells in lung.
Function:
Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
Subunit:
Interacts with ATP-bound HSP70 proteins. Interacts with NUP62 and NUP153 (via F-X-F-G repeats).
Subcellular Location:
Cytoplasm, cytosol. Nucleus.
Similarity:
Belongs to the OPI10 family.
Database links:
Entrez Gene: 51501 Human
Omim: 614908 Human
SwissProt: Q53FT3 Human
Unigene: 283322 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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