Rabbit Anti-FAR1/FITC Conjugated antibody

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Fatty acyl-CoA reductase 1; Fatty acyl CoA reductase 1; FAR1; FAR-1; FACR1_HUMAN.

Cat:

SL9437R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human FAR1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

59kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The conversion of fatty acids to fatty alcohols is required for the synthesis of wax monoesters and ether lipids. Members of the fatty acyl-CoA reductase family, including FAR1 (fatty acyl-CoA reductase 1) and FAR2 (fatty acyl-CoA reductase 2), play a role in catalyzing the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols. FAR1, also known as male sterility domain-containing protein 2 (MLSTD2) or short chain dehydrogenase/reductase family 10E, member 1 (SDR10E1), is a 515 amino acid single-pass membrane protein that localizes to the peroxisome, FAR1 is suggested to be essential for providing fatty alcohols required for ether bond formation in ether glycerophospholipid synthesis. The gene encoding FAR1 is located on chromosome 11, which comprises nearly 4% of the human genome.

Function:
Catalyzes the reduction of saturated fatty acyl-CoA with chain length C16 or C18 to fatty alcohols.

Subcellular Location:
Peroxisome membrane; Single-pass membrane protein (Potential).

Similarity:
Belongs to the fatty acyl-CoA reductase family.

Database links:

Entrez Gene: 84188 Human

SwissProt: Q8WVX9 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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