Rabbit Anti-GALR1/FITC Conjugated antibody

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GAL1R; galanin receptor 1; Galanin receptor; Galanin receptor type 1; GALNR; GALNR1; GALR1; GALR1_HUMAN.

Cat:

SL9927R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human GALR1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

39kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
GALR1 is a G-protein-coupled receptor for the neuropeptide galanin that influences endocrine secretions, intestinal motility, memory, weight, and pain perception. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, and in peripheral sites such as the small intestine and heart. The rat galanin receptor cDNA cloned from an insulinoma cell line is a predicted 346-amino acid G protein-coupled receptor with 92% homology to the human GALR1.

Function:
Receptor for the hormone galanin. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

Subcellular Location:
Cell Membrane; multi pass membrane protein

Post-translational modifications:
Palmitoylated on at least one of the three cysteine residues present in the SLCterminal part.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2587 Human

Entrez Gene: 14427 Mouse

Omim: 600377 Human

SwissProt: P47211 Human

SwissProt: P56479 Mouse

Unigene: 272191 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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