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Rabbit Anti-HGFA/FITC Conjugated antibody
background:
HGF activator belongs to the peptidase family S1 and activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form. HGF Activator is produced as a zymogen, and the form found in serum is largely the inactive single-chain form. It is activated to a heterodimeric form by endoproteolytic processing.
Function:
Activates hepatocyte growth factor (HGF) by converting it from a single chain to a heterodimeric form.
Subunit:
Heterodimer of a short chain and a long chain linked by a disulfide bond.
Subcellular Location:
Secreted. Note=Secreted as an inactive single-chain precursor and is then activated to a heterodimeric form.
Tissue Specificity:
Liver.
Similarity:
Belongs to the peptidase S1 family.
Contains 2 EGF-like domains.
Contains 1 fibronectin type-I domain.
Contains 1 fibronectin type-II domain.
Contains 1 kringle domain.
Contains 1 peptidase S1 domain.
Database links:
Entrez Gene: 6692 Human
Omim: 605123 Human
SwissProt: O43278 Human
Unigene: 233950 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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