background:
HPR is a ubiquitous transcription factor required for a diverse set of processes. It is a component of the CCR4 complex involved in the control of gene expression.
Subcellular Location:
Secreted.
Tissue Specificity:
In adult liver the amount of HPR mRNA is at the lower limit of detection, therefore the extent of its expression is at most less than 1000-fold that of the HP1F gene. No HPR mRNA can be detected in fetal liver. Expressed in Hep-G2 and leukemia MOLT-4 cell lines.
Similarity:
Belongs to the peptidase S1 family.
Contains 1 peptidase S1 domain.
Contains 1 Sushi (CCP/SCR) domain.
Database links:
Entrez Gene: 100442472 Human
Entrez Gene: 3250 Human
Omim: 140210 Human
SwissProt: P00739 Human
Unigene: 655361 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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