Home > Product > Antibody > Rabbit Anti-GGT6/FITC Conjugated antibody
Gamma glutamyltransferase 6 homolog; Gamma glutamyltranspeptidase 6; GGT 6; GGT6_HUMAN.
Cat:
SL9909R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human GGT6
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
50kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
GGT6 belongs to the gamma-glutamyltransferase family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis. GGT6 has very limited amino acid similarity to GGT1 and it's enzymatic activities are currently uncharacterized. GGT assays are of current widespread clinical use to help assess tissue damage.

Function:
Cleaves glutathione conjugates

Subunit:
Heterodimer composed of the light and heavy chains. The active site is located in the light chain (By similarity).

Subcellular Location:
Membrane; Single-pass type II membrane protein.

Similarity:
Belongs to the gamma-glutamyltransferase family.

Database links:

Entrez Gene: 124975 Human

Omim: 612341 Human

SwissProt: Q6P531 Human

Unigene: 130749 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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