Rabbit Anti-IGFALS/FITC Conjugated antibody

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Albs; IGFALS; Insulin like growth factor binding protein acid labile subunit; Insulin like growth factor binding protein complex acid labile chain; MGC150140; MGC150141; KIAA4111; mKIAA4111; ALS_HUMAN.

Cat:

SL9904R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human IGFALS

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

63kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The Insulin-like growth factor binding proteins, or IGFBPs, are a family of seven proteins that have co-evolved with the IGFs. IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, concentration and distribution of IGFs in the extracellular environment. In human circulation, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), an extracellular protein involved in receptor-ligand binding and cell adhesion. ALS, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein complexes.

Function:
Involved in protein-protein interactions that result inprotein complexes, receptor-ligand binding or cell adhesion.

Subunit:
Forms a ternary complex of about 140 to 150 kDa withIGF-I or IGF-II and IGFBP-3.

Subcellular Location:
Secreted; extracellular space.

Tissue Specificity:
Plasma.

Similarity:
Contains 19 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
Contains 1 LRRNT domain.

Database links:

Entrez Gene: 3483 Human

Omim: 601489 Human

SwissProt: P35858 Human

Unigene: 839 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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