Home > Product > Antibody > Rabbit Anti-Salusin alpha/FITC Conjugated antibody
Prosalusin precursor; TOR2A; TORP1; Torsin 2A [Precursor]; Torsin family 2 member A; Torsin related protein 1; TOR2A_HUMAN.
Cat:
SL9875R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,)
Immunogen:
KLH conjugated synthetic peptide derived from human Salusin alpha
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
33kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Salusins are multifunctional bioactive peptides discovered by bioinformatics analyses of a full-length cDNA library. Salusin alpha and salusin beta are related peptides of 28 and 20 amino acids that were recently characterized. These peptides are considered to be biosynthesized from preprosalusin, an alternative-splicing product of the torsion dystonia-related gene (TOR2A), after frameshift reading and digestion at dibasic amino acids. Salusin alpha has recently been shown to be involved in atherosclerosis; it potently suppresses acyl-CoA:cholesterol acyltransferase-1 which stores cholesterol ester converted from free cholesterol in macrophages, thereby reducing human macrophage foam cell formation.

Subcellular Location:
Secreted.

Tissue Specificity:
Isoform 1 is expressed ubiquitously, except in cardiac and endothelial tissues.

Similarity:
Belongs to the clpA/clpB family. Torsin subfamily.

Database links:

Entrez Gene: 27433 Human

Omim: 608052 Human

SwissProt: Q5JU69 Human

Unigene: 444106 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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