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Rabbit Anti-MYL7/FITC Conjugated antibody
background:
Encoded by the MYL7 gene, myosin regulatory light chain 7, also designated Myosin regulatory light chain 2, atrial isoform (MLSLC2a), is part of a hexameric complex of two heavy chains and four light chains predominantly expressed in adult atrial muscle. Myosin regulatory light chain 7 binds calcium and has been shown to be a useful molecular marker for cardiac chamber specification. The co-expression of myosin regulatory light chain 7 and myosin light chain 2 (MLC2v) in the outflow tract and atrioventricular canal, together with the single expression in the atrial (MYL7) and ventricular (MYL2) myo-cardium, permits the delineation of their boundaries. At the amino acid level there is 95% homology between the human and mouse myosin regulatory light chain 7 sequences.
Subunit:
Myosin is an hexamer of 2 heavy chains and 4 light chains.
Tissue Specificity:
Predominantly expressed in adult atrial muscle.
Similarity:
Contains 3 EF-hand domains.
Database links:
Entrez Gene: 58498 Human
Omim: 612147 Human
SwissProt: Q01449 Human
Unigene: 75636 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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