Home > Product > Antibody > Rabbit Anti-MYOM1/FITC Conjugated antibody
190 kDa connectin-associated protein; 190 kDa titin-associated protein; EH myomesin; MGC134946; MGC134947; MYOM1; MYOM1_HUMAN; Myomesin 1 185kDa; Myomesin family member 1; Myomesin-1; Skelemin.
Cat:
SL9863R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human MYOM1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
188kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Myomesin-1 and myomesin-2 are components of the vertebrate myofibrillar M band and are associated with Titin, Myosin and Connectin. The myomesin proteins are responsible for the formation of a head structure on one end of the Titin string that connects the Z and M bands of the sarcomere. Myomesin-1 and -2 have unique N-terminal domains and are expressed mainly in skeletal muscle. The gene encoding human myomesin-1 maps to chromosome 18p11.31-p11.32.

Function:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Subunit:
Interacts with TTN/titin (By similarity). Interacts with PNKD.

Tissue Specificity:
Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.

Similarity:
Contains 5 fibronectin type-III domains.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

Database links:

Entrez Gene: 8736 Human

Omim: 603508 Human

SwissProt: P52179 Human

Unigene: 464469 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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