background:
C3orf23, also known as FLJ41686, MGC119530, MGC119531, MGC119532, MGC119533 or DKFZp313N062, is a 496 amino acid protein that exists as four alternatively spliced isoforms. C3orf23 is encoded by a gene mapping to human chromosome 3p21.33. Chromosome 3 is made up of approximately 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Function:
May regulate T-cell apoptosis (By similarity).
Subcellular Location:
Mitochondrion (By similarity).
Database links:
Entrez Gene: 285343 Human
SwissProt: Q8N3R3 Human
SwissProt: Q66JZ4 Mouse
Unigene: 55131 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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