Rabbit Anti-MYH9/FITC Conjugated antibody

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non-muscle Myosin IIA; Myosin heavy polypeptide 9 non muscle; Myosin-9; Myosin9; Myosin 9; Alternative namesnon-muscle IIa; type A; Cellular myosin heavy chain; Cellular myosin heavy chain type A; DFNA 17; DFNA17; EPSTS; FTNS; MHA; MYH 2A; MYH 9; MYH9; MY

Cat:

SL9610R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Pig,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human MYH9

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

226kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. Defects in MYH9 are the cause of May-Hegglin anomaly (MHA) . MHA is an autosomal dominant macrothrombocytopenia characterized by thrombocytopenia, giant platelets and leukokyte inclusions appearing as highly parallel paracrystalline bodies.

Function:
Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping.

Subunit:
Interacts with PDLIM2. Interacts with SLC6A4. Myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLSLC2). Interacts with RASIP1. Interacts with DDR1. Interacts with SVIL and HTRA3.

Subcellular Location:
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.

Tissue Specificity:
In the kidney, expressed in the glomeruli. Also expressed in leukocytes.

Post-translational modifications:
ISGylated.

Similarity:
Contains 1 IQ domain.
Contains 1 myosin head-like domain.

Database links:

Entrez Gene: 4627 Human

Entrez Gene: 17886 Mouse

Entrez Gene: 25745 Rat

Omim: 160775 Human

SwissProt: P35579 Human

SwissProt: Q8VDD5 Mouse

SwissProt: Q62812 Rat

Unigene: 474751 Human

Unigene: 29677 Mouse

Unigene: 2285 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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