Rabbit Anti-FGF18/FITC Conjugated antibody

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FGF 18; FGF18; FGF-18; Fibroblast Growth Factor 18; ZFGF5; FGF18_HUMAN.

Cat:

SL9762R-FITC

Species Reactivity：

Mouse,(predicted: Human,Rat,Chicken,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human FGF18

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

21kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
FGF18 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Function:
Plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. Required for normal ossification and bone development. Stimulates hepatic and intestinal proliferation.

Subunit:
Interacts with FGFR3 and FGFR4.

Subcellular Location:
Secreted

Similarity:
Belongs to the heparin-binding growth factors family.

Database links:

Entrez Gene: 8817 Human

Entrez Gene: 14172 Mouse

Entrez Gene: 29369 Rat

Omim: 603726 Human

SwissProt: Q0VCA0 Cow

SwissProt: O76093 Human

SwissProt: O89101 Mouse

SwissProt: O88182 Rat

Unigene: 87191 Human

Unigene: 339812 Mouse

Unigene: 44478 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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