Home > Product > Antibody > Rabbit Anti-ANGEL1/FITC Conjugated antibody
ANGE1_HUMAN; ANGEL1; KIAA0759; mKIAA0759; Protein angel homolog 1; angel homolog 1; RGD1306238.
Cat:
SL9741R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human ANGEL1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
75kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
ANGEL1 , also known as KIAA0759, is a 670 amino acid protein belonging to the CKR-4 protein family. ANGEL1 is encoded by a gene located on human chromosome 14, which contains about 700 genes and 106 million base pairs, making up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and, when defective, leads to the genetic disorder ?-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus on chromosome 14 and its fusion via translocation with the chromosome 19 encoded protein BCL3 may be related to B-cell malignancies.

Similarity:
Belongs to the CCR4/nocturin family.

Database links:

Entrez Gene: 23357 Human

Entrez Gene: 68737 Mouse

SwissProt: Q9UNK9 Human

SwissProt: Q8VCU0 Mouse

Unigene: 497448 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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