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Home > Product > Antibody > Rabbit Anti-NOP2/FITC Conjugated antibody
Proliferation Associated Nucleolar Antigen: NOL 1; NUCLEOLAR ANTIGEN p120; NOP2_HUMAN.
Cat:
SL9710R-FITC
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Rabbit,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human NOL1
Format：
Lyophilized or Liquid
Storage instructions：
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer：
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
Calculated MW：
89kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
Proliferation-associated nucleolar antigen is expressed in mid G1 phase with peak level during the S phase and a rapid degradation during late mitosis. Its expression in breast carcinoma is correlated with patient prognosis.

Function:
May play a role in the regulation of the cell cycle andthe increased nucleolar activity that is associated with the cellproliferation. May act as ribosomal RNA methyltransferase.

Subunit:
Interaction with MCRS1.

Subcellular Location:
Nuclear

Similarity:
Belongs to the methyltransferase superfamily. RsmB/NOPfamily.

Database links:

Entrez Gene: 4839 Human

Entrez Gene: 110109 Mouse

Entrez Gene: 314969 Rat

Omim: 112831 Human

SwissProt: P9287 Human

SwissProt: Q922K7 Mouse

Unigene: 534334 Human

Unigene: 29203 Mouse

Unigene: 32804 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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