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Rabbit Anti-Kazrin/FITC Conjugated antibody
background:
Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known.
Function:
Component of the cornified envelope of keratinocytes.May be involved in the interplay between adherens junctions anddesmosomes. The function in the nucleus is not known.
Subunit:
Isoform 2, isoform 3 and isoform 4 interact with PPLN-terminus.
Subcellular Location:
Cytoplasm
Tissue Specificity:
Isoform 2, isoform 3 and isoform 4 are expressed in several cell lines including keratinocytes and bladder and epidermoid carcinoma (at protein level). Isoform 2, isoform 3 and isoform 4 are expressed in hair follicle and interfollicular epidermis (at protein level).
Similarity:
Belongs to the kazrin family.
Contains 3 SAM (sterile alpha motif) domains
Database links:
Entrez Gene: 23254 Human
Entrez Gene: 71529 Mouse
Entrez Gene: 313672 Rat
SwissProt: Q674X7 Human
SwissProt: Q69ZS8 Mouse
SwissProt: Q5FWS6 Rat
Unigene: 368823 Human
Unigene: 255986 Mouse
Unigene: 3753 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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