Rabbit Anti-ITM2A/FITC Conjugated antibody

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BRICD2A; BRICHOS domain containing 2A; E25 protein; E25A; Integral membrane protein 2A; ITM2A; ITM2A_HUMAN; Protein E25.

Cat:

SL9705R-FITC

Species Reactivity：

Human,(predicted: Mouse,Rat,Pig,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human ITM2A

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

Flow-Cyt=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

30kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The type II integral membrane (ITM2) protein family consists of three members ITM2A (also designated E25), ITM2B and ITM2C. ITM2A expression is high in osteogenic and lymphoid tissues, while both ITM2B and ITM2C are expressed in brain. Mutations in the ITM2B gene can lead to familial British dementia (fbd), and autosomal dominant disease characterized by progressive dementia, spasticity, and cerebellar ataxia, or familial Danish dementia (fdd), an autosomal dominant disorder characterized by cataracts, deafness, progressive ataxia, and dementia. The ITM2A 263-amino acid protein contains an N-terminal cytosolic domain, an uncleaved signal anchor sequence, and a tyrosine-rich SLCterminal domain. Human ITM2A shares 91% homology with mouse ITM2A.

Subcellular Location:
Membrane; Single-pass type II membraneprotein (Potential).

Similarity:
Belongs to the ITM2 family.
Contains 1 BRICHOS domain.

Database links:

Entrez Gene: 9452 Human

Omim: 300222 Human

SwissProt: O43736 Human

Unigene: 17109 Human

Unigene: 694944 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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