Home > Product > Antibody > Rabbit Anti-TSPAN16/FITC Conjugated antibody
Tetraspanin TM4-B; Tetraspanin-16; TM 8; TM4 B; TM4SF16; Transmembrane 4 superfamily member 16; TSN16_HUMAN; Tspan-16; TSPAN16.
Cat:
SL9423R-FITC
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human TSPAN16/TM4-B
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
26kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
TM4-B, also known as TSPAN16 (tetraspanin-16) or TM4SF16 (transmembrane 4 superfamily member 16), is a 245 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the TM4SF family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4-B is broadly expressed in most human tissues and cell lines including neural and bone marrow derived tissues. The gene that encodes TM4-B contains nearly 31,000 bases and maps to human chromosome 19p13.2. Chromosome 19 consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families and Fc receptors (FcRs).

Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).

Tissue Specificity:
Broadly expressed in most human tissues and cell lines including neural and bone marrow derived tissues.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Database links:

Entrez Gene: 26526 Human

SwissProt: Q9UKR8 Human

Unigene: 579784 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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