Home
>
Product
>
Antibody
>
Rabbit Anti-TSPAN13/FITC Conjugated antibody
background:
NET-6, also known as TSPAN13 (tetraspanin-13) or TM4SF13 (transmembrane 4 superfamily member 13), is a 204 amino acid multi-pass membrane protein that belongs to the tetraspanin (TM4SF) family. Members of the tetraspanin family are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth, motility, differentiation, and cancer. Considered molecular facilitators, tetraspanin proteins may regulate vesicle fusion and fission. The gene encoding NET-6 maps to human chromosome 7, which houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).
Similarity:
Belongs to the tetraspanin (TM4SF) family.
Database links:
Entrez Gene: 27075 Human
Entrez Gene: 66109 Mouse
Entrez Gene: 366602 Rat
Omim: 613139 Human
SwissProt: Q3ZBV0 Cow
SwissProt: O95857 Human
SwissProt: Q9D8C2 Mouse
SwissProt: Q5FVL6 Rat
Unigene: 49488 Cow
Unigene: 21306 Dog
Unigene: 364544 Human
Unigene: 254663 Mouse
Unigene: 24284 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
|
|