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Rabbit Anti-TSPAN4/FITC Conjugated antibody
background:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
Subunit:
Forms a complex with integrins.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in multiple tissues but is absent in brain, lymphoid cells, and platelets.
Similarity:
Belongs to the tetraspanin (TM4SF) family.
Database links:
Entrez Gene: 7106 Human
Omim: 602644 Human
SwissProt: O14817 Human
Unigene: 654836 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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