Rabbit Anti-TSPAN3/FITC Conjugated antibody

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tetraspanin 3; tetraspanin TM4 A; TM4 A; TM4A; TM4SF8; transmembrane 4 superfamily member 8; TSPAN 3; TSPAN-3; TSPAN3; TSN3_HUMAN.

Cat:

SL9412R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TSPAN3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

28kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
TSPAN3 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.

Function:
Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.

Subunit:
Interacts with claudin-11/CLDN11 and integrins.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Database links:

Entrez Gene: 10099 Human

Entrez Gene: 56434 Mouse

Omim: 613134 Human

SwissProt: Q3SZR9 Cow

SwissProt: O60637 Human

SwissProt: Q9QY33 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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