Rabbit Anti-EDPF1/MMS2/FITC Conjugated antibody

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1 alpha 25 dihydroxyvitamin D3 inducible; DDVit 1; DDVIT1; EDAF-1; EDAF1; EDPF-1; EDPF1; Enterocyte differentiation associated factor EDAF 1; Enterocyte differentiation promoting factor; Enterocyte differentiation-associated factor 1; Enterocyte different

Cat:

SL9377R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human MMS2/EDPF1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

16kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Function:
Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

Subunit:
Heterodimer with UBE2N. Binds CHFR.

Tissue Specificity:
Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues.

Similarity:
Belongs to the ubiquitin-conjugating enzyme family.

Database links:

Entrez Gene: 281363 Cow

Entrez Gene: 608470 Dog

Entrez Gene: 7336 Human

Entrez Gene: 100503412 Mouse

Entrez Gene: 70620 Mouse

Entrez Gene: 100627960 Pig

Entrez Gene: 287927 Rat

Entrez Gene: 380089 Xenopus laevis

Entrez Gene: 406836 Zebrafish

Omim: 603001 Human

SwissProt: Q3SZ43 Cow

SwissProt: Q15819 Human