Rabbit Anti-PSMD7/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-PSMD7/FITC Conjugated antibody

26S proteasome non ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit rpn8; 26S proteasome regulatory subunit S12; Moloney leukemia virus 34 proviral integration; MOV 34; MOV 34L; MOV34; Mov34 ho

Cat:

SL9366R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PSMD7

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

37kDa

prev next

Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

background:
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.

Function:
Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.

Subunit:
Homodimer. Interacts with TRIM5.

Similarity:
Belongs to the peptidase M67A family.
Contains 1 MPN (JAB/Mov34) domain.

Database links:

Entrez Gene: 5713 Human

Entrez Gene: 17463 Mouse

Entrez Gene: 307821 Rat

Omim: 157970 Human

SwissProt: Q3ZBD0 Cow

SwissProt: P51665 Human

SwissProt: P26516 Mouse

Unigene: 88604 Human

Unigene: 18347 Mouse

Unigene: 20659 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Product Feedback Wall