Rabbit Anti-Proteasome 20S beta 6/FITC Conjugated antibody

Home > Product > Antibody > Rabbit Anti-Proteasome 20S beta 6/FITC Conjugated antibody

Delta; LMPY; Macropain delta chain; MGC5169; Multicatalytic endopeptidase complex delta chain; Proteasome (prosome macropain) subunit beta type 6; Proteasome beta 6 subunit; Proteasome catalytic subunit 1; Proteasome delta chain; Proteasome subunit beta 6

Cat:

SL9358R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,)

Immunogen：

KLH conjugated synthetic peptide derived from human Proteasome 20S beta 6

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

22kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Function:
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This unit is responsible of the peptidyl glutamyl-like activity. May catalyze basal processing of intracellular antigens.

Subunit:
The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel. This subunit can be displaced by the equivalent immune-specific subunit PSMB9. Interacts with HISLV1 TAT protein.

Subcellular Location:
Cytoplasm. Nucleus.

Similarity:
Belongs to the peptidase T1B family.

Database links:

Entrez Gene: 5694 Human

Entrez Gene: 19175 Mouse

Entrez Gene: 29666 Rat

Omim: 600307 Human

SwissProt: P28072 Human

SwissProt: Q60692 Mouse

SwissProt: P28073 Rat

Unigene: 77060 Human

Unigene: 98 Mouse

Unigene: 8118 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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