Rabbit Anti-PSMC2/Proteasome 19S S7/FITC Conjugated antibody

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26S protease complex; 26S protease regulatory subunit 7; 26S proteasome AAA-ATPase subunit RPT1; mammalian suppressor of sgv-1 of yeast; MSS1; Nbla10058; protease 26S subunit 7; proteasome 26S ATPase subunit 2; Proteasome 26S subunit ATPase 2; proteasome

Cat:

SL9349R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human Proteasome 19S S7

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

49kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HISLV1 infection, positive modulator of Tat-mediated transactivation.

Function:
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HISLV1 infection, positive modulator of Tat-mediated transactivation.

Subunit:
Interacts with NDC80 and SQSTM1. Interacts with PAAF1. Interacts with HISLV1 Tat. Interacts with TRIM5.

Subcellular Location:
Cytoplasm. Nucleus. Cytoplasm, P-body (By similarity). Note=Co-localizes with TRIM5 in the cytoplasmic bodies (By similarity).

Similarity:
Belongs to the AAA ATPase family.

Database links:

Entrez Gene: 5701 Human

Entrez Gene: 19181 Mouse

Entrez Gene: 25581 Rat

Omim: 154365 Human

SwissProt: P35998 Human

SwissProt: P46471 Mouse

SwissProt: Q63347 Rat

Unigene: 437366 Human

Unigene: 2462 Mouse

Unigene: 1202 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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