Home > Product > Antibody > Rabbit Anti-NHLRC3/FITC Conjugated antibody
DKFZp313M1221; DKFZp686E1140; NHL repeat containing 3; NHL repeat containing protein 3; NHLRC 3; NHLC3_HUMAN.
Cat:
SL9333R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human NHLRC3
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
35kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
NHLRC3 contains 4 NHL repeats. The function of the NHLRC3 protein remains unknown. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.

Subcellular Location:
Secreted

Similarity:
Contains 4 NHL repeats.

Database links:

Entrez Gene: 387921 Human

Entrez Gene: 212114 Mouse

Entrez Gene: 310416 Rat

SwissProt: Q5JS37 Human

SwissProt: Q8CCH2 Mouse

Unigene: 507783 Human

Unigene: 85744 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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