Rabbit Anti-LRCH4/LRRN1/FITC Conjugated antibody

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Leucine rich repeat neuronal protein 4; Leucine rich repeats and calponin homology (CH) domain containing 4; Leucine-rich neuronal protein; LRN; LRRN1; LRRN4; PP14183; SAP25; Sin3 associated polypeptide, 25kDa; LRCH4_HUMAN.

Cat:

SL9330R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human LRCH4

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

73kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Members of the leucine-rich repeat family include LRCH1, LRCH2, LRCH3 and LRCH4. All family members contain one calponin-homology domain and nine leucine-rich repeats. LRCH4 (leucine-rich repeats and calponin homology (CH) domain containing 4), also known as LRN, LRRN1, LRRN4 or SAP25, is a 683 amino acid protein that belongs to the leucine-rich repeat family. The carboxy-terminus of LRCH4 may act as a membrane anchor between cells, while the amino-terminus contains the leucine-rich domains, which is thought to be involved in ligand binding. The calponin homology (CH) domain is suggested to confer Actin binding to a variety of cytoskeletal and signaling molecules. The gene encoding LRCH4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 9 LRR (leucine-rich) repeats.

Database links:

Entrez Gene: 4034 Human

Entrez Gene: 231798 Mouse

Entrez Gene: 100516002 Pig

Entrez Gene: 72779 Rat

SwissProt: O75427 Human

SwissProt: Q921G6 Mouse

Unigene: 125742 Human

Unigene: 200763 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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