Rabbit Anti-NYS48/FITC Conjugated antibody

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HAUS augmin like complex subunit 8; Hec1 interacting and centrosome associated 1; HEC1/NDC80 interacting centrosome associated protein 1; HICE 1; HICE1; MGC20533; NY SAR 48; Sarcoma antigen NY SAR 48; HAUS8_HUMAN.

Cat:

SL964R-FITC

Species Reactivity：

(predicted: Human,Mouse,)

Immunogen：

KLH conjugated synthetic peptide derived from human NYS48

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
NYS48 belongs to the HAUS8 family. It is required for stabilizing spindle integrity and chromosomal integrity.

Function:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.

Subunit:
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly. Associates with microtubules. The interaction with microtubules is strong during mitosis, while it is weak or absent during interphase. It is unclear whether this interaction is direct or indirect.

Subcellular Location:
Cytoplasm, cytoskeleton, Microtubule.

Similarity:
Belongs to the HAUS8 family.

Database links:

Entrez Gene: 93323 Human

Omim: 613434 Human

SwissProt: Q9BT25 Human

Unigene: 404088 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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