Rabbit Anti-C21orf106/DIP2A/FITC Conjugated antibody

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C21orf106; DIP 2A; DIP2; DIP2 disco interacting protein 2 homolog A; DIP2 homolog A; DIP2A; DIP2 like protein; Disco interacting protein 2 homolog; KIAA0184; DIP2A_HUMAN.

Cat:

SL9312R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Cow,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DIP2A/C21orf106

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

170kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
DIP2A, also known as DIP2, is a 1571 amino acid nuclear protein. It is one of three human homologs (DIP2A, DIP2B and DIP2C) of the Drosophila dip2 (disconnected-interacting protein 2) protein. In Drosophila, dip2 interacts with disco, a protein required for neuronal connections in the visual systems of larvae and adults. The closest vertebrate homologs to disco are the basonuclin genes. In mice, DIP2 homologs show restricted expression to the brain. This suggests that, similar to the function of Drosophila dip2, vertebrate DIP2 homologs may play a role in the development of the nervous system. Expressed ubiquitously with highest expression in the brain, DIP2A is thought to function in signaling throughout the central nervous system by providing positional clues for axon patterning and pathfinding. Four isoforms of DIP2A exist due to alternative splicing events.

Function:
May provide positional cues for axon pathfinding and patterning in the central nervous system.

Subcellular Location:
Nuclear

Tissue Specificity:
Low expression in all tissues tested.

Similarity:
Belongs to the DIP2 family.

Database links:

Entrez Gene: 23181 Human

Entrez Gene: 64451 Mouse

Omim: 607711 Human

SwissProt: Q14689 Human

SwissProt: Q8BWT5 Mouse

Unigene: 189585 Human

Unigene: 33183 Mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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