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Rabbit Anti-SERPINB12/FITC Conjugated antibody
background:
The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SERPINB12 appears to be an inhibitor of trypsin-like serine proteinases, including mast cell tryptases.
Function:
Inhibits trypsin and plasmin, but not thrombin, coagulation factor Xa, or urokinase-type plasminogen activator.
Subcellular Location:
Cytoplasmic
Tissue Specificity:
Expressed in many tissues, including brain, bone marrow, lymph node, heart, lung, liver, pancreas, testis, ovary, and intestine.
Similarity:
Belongs to the serpin family. Ov-serpin subfamily.
Database links:
Entrez Gene: 89777 Human
SwissProt: Q96P63 Human
Unigene: 348541 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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