Rabbit Anti-SERPINB10/FITC Conjugated antibody

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Bomapin; PI10; Protease inhibitor 10; Protease inhibitor 10 (ovalbumin type bomapin); Serpin B10; Serpin peptidase inhibitor clade B (ovalbumin) member 10; SPB10_HUMAN.

Cat:

SL9211R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human SERPINB10

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
SERPINB10 is a serine proteinase inhibitor of the ovalbumin like B clade of serpins. It was first discovered in human bone marrow in a search for serpins similar to SerpinB6. SERPINB10 was identified in lymphocytes, and was elevated in chronic myeloid leukemia and chronic myelomonocytic leukemia cells. The monocytic cell lines THP-1 and AML-193 also showed elevated SERPINB10 expression.

Function:
Protease inhibitor that may play a role in the regulation of protease activities during hematopoiesis and apoptosis induced by TNF. May regulate protease activities in the cytoplasm and in the nucleus.

Subcellular Location:
Nucleus. Cytoplasm.

Tissue Specificity:
Expressed specifically in the bone marrow.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

Database links:

Entrez Gene: 5273 Human

GenBank: NP_005015.1 Human

Omim: 602058 Human

SwissProt: P48595 Human

SwissProt: Q4VAX7 Human

Unigene: 158339 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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