Home > Product > Antibody > Rabbit Anti-IGSF16/FITC Conjugated antibody
CD300 antigen-like family member C; CD300c; CLM-6; CLM6_HUMAN; CMRF-35; CMRF35 leukocyte immunoglobulin-like receptor; CMRF35-A1; CMRF35-like molecule 6; CMRF35A leukocyte immunoglobulin-like receptor; IgSF16; Immunoglobulin superfamily member 16; LIR.
Cat:
SL9203R-FITC
Species Reactivity:
(predicted: Human,)
Immunogen:
KLH conjugated synthetic peptide derived from human IGSF16/CD300C
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
23kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
CD300C (), also known as CLM-6 (CMRF35-like molecule 6), is a 224 amino acid single-pass type I membrane protein that is present on the surface of neutrophils, monocytes and a select proportion of peripheral blood B and T lymphocytes. CD300C contains two potential N-gylcosylation sites, a potential O-glycosylated hinge-like region and an Ig-like SLVtype (immunoglobulin-like) domain that is very similar to the Fc receptor for polymeric IgA and IgM. The gene encoding CD300C is localized to a region on human chromosome 17 that harbors a susceptilibty locus for psoriasis, dermatitis and rheumatoid arthritis, suggesting a possible involvement of CD300C with these conditions.

Subcellular Location:
Cell membrane

Tissue Specificity:
Present on the surface of monocytes, neutrophils, a proportion of peripheral blood T- and B-lymphocytes and lymphocytic cell lines.

Similarity:
Belongs to the CD300 family.
Contains 1 Ig-like SLVtype (immunoglobulin-like) domain.

Database links:

Entrez Gene: 10871 Human

Omim: 606786 Human

SwissProt: Q08708 Human

Unigene: 2605 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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