Home > Product > Antibody > Rabbit Anti-PROCA1/FITC Conjugated antibody
PRCA1_HUMAN; Proca1; proline-rich cyclin A1-interacting protein; Protein interacting with cyclin A1; Protein PROCA1; RP23-185A18.6.
Cat:
SL9188R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human PROCA1
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
41kDa
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Unit:
Price: $
Product PDFs
Datasheet:


background:
PROCA1 is a 364 amino acid protein that belongs to the PROCA1 family and exists as two alternatively spliced isoforms. Conserved in dog, cow, mouse and rat, PROCA1 participates in calcium ion binding and phospholipase A2 activity. The gene that encodes PROCA1 maps to human chromosome 17q11.2. Chromosome 17 makes up over 2.5% of the human genome, with approximately 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. BRCA1 is recognized as a genetic determinant of early onset breast cancer. Chromosome 17 is also linked to neurofibromatosis, dysregulated Schwann cell growth, Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease。

Similarity:
Belongs to the PROCA1 family.

Database links:

Entrez Gene: 147011 Human

SwissProt: Q8NCQ7 Human

Unigene: 207471 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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