Rabbit Anti-RNF22/TRIM3/FITC Conjugated antibody

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TRIM3; BERP; Brain expressed RING finger protein; FLJ16135; HAC1; Ring finger protein 22; RNF22; RNF9; Tripartite motif containing 3

Cat:

SL9174R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human TRIM3/RNF22

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

81kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
BERP; Brain expressed RING finger protein; FLJ16135; HAC1; Ring finger protein 22; RNF22; RNF9; Tripartite motif containing 3.

Function:
Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation.

Subunit:
Associates with myosin-Vb (MYO5B) and alpha-actinin-4 (ACTN4) (By similarity). Component of the CART complex, at least composed of ACTN4, HGS/HRS, MYO5B and TRIM3. Interacts with ZFYVE28/LST2.

Subcellular Location:
Cytoplasmic

Tissue Specificity:
Expressed in brain, heart, uterus and testis.

Similarity:
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 filamin repeat.
Contains 6 NHL repeats.
Contains 1 RING-type zinc finger.

Database links:

Entrez Gene: 10612 Human

Entrez Gene: 55992 Mouse

Entrez Gene: 83616 Rat

Omim: 605493 Human

SwissProt: O75382 Human

SwissProt: Q9R1R2 Mouse

SwissProt: O70277 Rat

Unigene: 591992 Human

Unigene: 29290 Mouse

Unigene: 203982 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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