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Rabbit Anti-TRIM35/FITC Conjugated antibody
background:
TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2 and a coiled-coil region. TRIM35 may play a role as a tumor suppressor and is implicated in the cell death mechanism. There are two named isoforms.
Function:
May play a role as a tumor suppressor. Implicated in the cell death mechanism (By similarity).
Subcellular Location:
Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies.
Similarity:
Belongs to the TRIM/RBCC family.
Contains 1 B box-type zinc finger.
Contains 1 B30.2/SPRY domain.
Contains 1 RING-type zinc finger.
Database links:
Entrez Gene: 23087 Human
Entrez Gene: 66854 Mouse
Entrez Gene: 498538 Rat
SwissProt: Q9UPQ4 Human
SwissProt: Q8C006 Mouse
SwissProt: Q5RKG6 Rat
Unigene: 104223 Human
Unigene: 43871 Mouse
Unigene: 15796 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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