Rabbit Anti-FBXO27/FITC Conjugated antibody

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F-box G-domain protein 5; F-box only protein 27; F-box protein 27; F-box protein FBG5; FBG5; Fbx27.

Cat:

SL9089R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human FBXO27

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

32kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin (CUL1), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.

Function:
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Able to recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides.

Subunit:
Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with SKP1 and CUL1.

Tissue Specificity:
Predominantly expressed in brain, heart and kidney. Expressed at lower levels in liver and lung.

Similarity:
Contains 1 F-box domain.
Contains 1 FBA (F-box associated) domain.

Database links:

Entrez Gene: 126433 Human

Entrez Gene: 233040 Mouse

Omim: 609099 Human

SwissProt: Q8NI29 Human

SwissProt: Q6DIA9 Mouse

Unigene: 187461 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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