Rabbit Anti-HSP1/FITC Conjugated antibody

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Cysteine-rich protamine; Protamine P1 PRM1; Sperm protamine P1; HSP1_HUMAN; Protamine P1.

Cat:

SL6447R-FITC

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human HSP1/Protamine P1

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

6kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex. Protamines are cross-linked by interchain disulfide bonds around the DNA-helix. Protamines are localised in the nucleus. This protein is found only in the testis and belongs to the protamine P1 family.

Function:
Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.

Subunit:
Cross-linked by interchain disulfide bonds around the DNA-helix.

Subcellular Location:
Nucleus. Chromosome.

Tissue Specificity:
Testis.

DISEASE:
Phosphorylated by SRPK1.

Similarity:
Belongs to the protamine P1 family.

Database links:

Omim: 182176 Human

SwissProt: P04553 Human

Unigene: 2909 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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