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Rabbit Anti-Mitoferrin 1/FITC Conjugated antibody
background:
Mitoferrin1, SLC25A37, belongs to the mitochondrial carrier family and contains 3 Solcar repeats. It is a mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells and plays an essential role in heme biosynthesis.
Function:
Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme.
Subcellular Location:
Mitochondrial inner membrane; Multi-pass membrane protein
Similarity:
Belongs to the mitochondrial carrier family.
Contains 3 Solcar repeats.
Database links:
Entrez Gene: 51312 Human
Omim: 610387 Human
SwissProt: Q9NYZ2 Human
Unigene: 596025 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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