Home > Product > Antibody > Rabbit Anti-PI14/FITC Conjugated antibody
MEPI; Myoepithelium derived serine protease inhibitor; Pancpin; Pancreas specific protein TSA2004; Peptidase inhibitor 14; PI 14; PI14; Protease inhibitor 14; Serine (or cysteine) proteinase inhibitor clade I (neuroserpin) member 2; Serine (or cysteine) p
Cat:
SL9514R-FITC
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Horse,)
Immunogen:
KLH conjugated synthetic peptide derived from human SERPINI2/PI14
Format:
Lyophilized or Liquid
Storage instructions:
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant
Buffer:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
Calculated MW:
44kDa
More
Unit:
Price: $
Product PDFs
Datasheet:


background:
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Subcellular Location:
Secreted

Tissue Specificity:
Expressed in pancreas and adipose tissues.

Similarity:
Belongs to the serpin family.

Database links:

Entrez Gene: 5276 Human

Entrez Gene: 67931 Mouse

Entrez Gene: 171149 Rat

Omim: 605587 Human

SwissProt: O75830 Human

SwissProt: Q9JK88 Mouse

Unigene: 445555 Human

Unigene: 259446 Mouse

Unigene: 54500 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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