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Rabbit Anti-PI14/FITC Conjugated antibody
background:
SERPINI2 is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. It may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.
Subcellular Location:
Secreted
Tissue Specificity:
Expressed in pancreas and adipose tissues.
Similarity:
Belongs to the serpin family.
Database links:
Entrez Gene: 5276 Human
Entrez Gene: 67931 Mouse
Entrez Gene: 171149 Rat
Omim: 605587 Human
SwissProt: O75830 Human
SwissProt: Q9JK88 Mouse
Unigene: 445555 Human
Unigene: 259446 Mouse
Unigene: 54500 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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