Rabbit Anti-DOM3Z/FITC Conjugated antibody

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Dom 3 homolog Z; DOM 3Z; Dom-3 homolog Z; DOM3 C. elegans homolog of Z; Dom3 homolog Z; DOM3L; Dom3z; DOM3Z_HUMAN; NG6; Protein Dom3Z.

Cat:

SL9054R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human DOM3Z

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

45kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
DOM3Z, also known as NG6 or DOM3L, is a 396 amino acid ubiquitously expressed protein belonging to the Dom3Z family. The gene encoding DOM3Z maps to human chromosome 6 in the major histocompatibility complex (MHC) class III region. Chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome are all associated with genes that map to chromosome 6.

Function:
May possess pyrophosphohydrolase activity towards 5' triphosphorylated RNA (By similarity).

Tissue Specificity:
Ubiquitously expressed

Similarity:
Belongs to the Dom3Z family.

Database links:

Entrez Gene: 50892 Cow

Entrez Gene: 1797 Human

Entrez Gene: 11483 Mouse

Entrez Gene: 100124385 Pig

Entrez Gene: 361799 Rat

Omim: 605996 Human

SwissProt: Q5E9Y5 Cow

SwissProt: O77932 Human

SwissProt: O70348 Mouse

SwissProt: Q6MG77 Rat

Unigene: 153299 Human

Unigene: 275309 Mouse

Unigene: 20463 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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