Rabbit Anti-PAR3/FITC Conjugated antibody

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Proteinase Activated Receptor 3; coagulation factor II (thrombin) receptor-like 2; Coagulation factor II receptor-like 2; F2RL2; PAR 3; PAR-3; PAR3; PAR3_HUMAN; protease activated receptor3; Proteinase-activated receptor 3; thrombin receptor like 2; Throm

Cat:

SL9510R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human PAR3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ICC=1:50-200IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

42kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.
Tissue specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Function:
Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.

Post-translational modifications:
A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

Database links:

Entrez Gene: 2151 Human

Omim: 601919 Human

SwissProt: Q58D85 Cow

SwissProt: O00254 Human

Unigene: 24447 Cow

Unigene: 136948 Human

Unigene: 42502 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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