Rabbit Anti-PDZD6/FITC Conjugated antibody

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Homolog of inturned (X. tropicalis); INT; intu; Inturned planar cell polarity effector homolog; KIAA1284; PDZ domain containing 6; PDZ domain-containing protein 6; PDZD 6; PDZD6_HUMAN; PDZK6.

Cat:

SL9041R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human PDZD6

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

106kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Function:
Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity).

Subcellular Location:
Cytoplasm (By similarity). Cell surface (By similarity). Note=Enriched at the apical surface in ciliated cells (By similarity).

Similarity:
Belongs to the inturned family.
Contains 1 PDZ (DHR) domain.

Database links:

Entrez Gene: 27152 Human

Entrez Gene: 380614 Mouse

Omim: 610621 Human

SwissProt: Q9ULD6 Human

SwissProt: Q059U7 Mouse

Unigene: 391481 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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