Rabbit Anti-NT-3/FITC Conjugated antibody

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HDNF; MGC129711; Nerve growth factor 2; Neurotrophic factor; Neurotrophin 3 precursor; Neurotrophin-3; Neurotrophin3; NGF 2; NGF-2; NGF2; NT 3; NT-3; NT3; NTF 3; NTF3; NTF3_HUMAN.

Cat:

SL4724R-FITC

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Cow,)

Immunogen：

KLH conjugated synthetic peptide derived from human NT-3

Format：

Lyophilized or Liquid

Storage instructions：

Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of ant

Buffer：

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IF=1:50-200not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

Calculated MW：

14/28kDa

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Unit:

Price: $596.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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background:
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq, Jul 2008].

Function:
Seems to promote the survival of visceral and proprioceptive sensory neurons.

Subcellular Location:
Secreted.

Tissue Specificity:
Brain and peripheral tissues.

Similarity:
Belongs to the NGF-beta family.

Database links:

Entrez Gene: 4908 Human

Entrez Gene: 18205 Mouse

Entrez Gene: 81737 Rat

Omim: 162660 Human

SwissProt: P20783 Human

SwissProt: P20181 Mouse

SwissProt: P18280 Rat

Unigene: 99171 Human

Unigene: 267570 Mouse

Unigene: 9715 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

一种内源型神经递质，分子量为28kDa的碱性多肽，属神经营养蛋白家族。与NGF和BDNF具有序列同源性，为培养的神经嵴细胞的促细胞分裂剂。此抗体与NGF、BDNF无交叉反应。

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